|Duration of treatment with Pegasus and Copegus
Dec 19, 2004
My husband is HIV pos (undetectable)and was on 48-week treatment for Hep C with Pegintron and Rebetol. Was off for three months, the Hep C came back, and his doctor put him on Pegasus alone. After five months on maintenance, he convinced his doctor to put him on Copegus also. My question is how long do you retreat using both Pegasus and Copegus. His doctor thinks 24 weeks, not 48 weeks since he was already on treatment for a year. However, he had a three month break. I'm a bit confused. How long should he be on Copegus with the shot the second time around? Could you please respond and let us know. Thank you very much.
Response from Dr. McGovern
It is excellent that your husband did attain viral suppression the first time around, since most likely his liver did get a histologic benefit - ie, the liver probably looks healthier under the microscope than it did before treatment.
When your husband was put on Pegasys alone, this was for "maintenance therapy." The idea here is that perhaps keeping a patient on low dose maintenance is healthier for the liver. However, keep in mind that this is not yet proven since we are still waiting for the results of studies. However, on a case by case basis many experts are doing this if the patient has severe liver disease.
A second trial of Pegasys and Copegus may not work any better than the first unfortunately. Some studies like "SLAM-C" are looking at whether longer treatment may be helpful but again, we do not know if this will work any better.
Over the next year or two more and more information will be coming out in this regard so stay tuned.
Glyburide & Metformin vs Insulin
Hepsera + Epivir
- Is Gum Pain An Early Symptom Of Hiv?
- Who Is Susceptible To Getting Hiv And Aids?
- Thrush And Severe Throat Pain
- What's The Difference Between Mouth Ulcers And Herpes Simplex 1?
- What If Antibiotics Did Not Clear Up My Bacterial Vaginosis?
- What Are The Different Types Of Herpes Zosters Or Shingles?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.