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Hepatitis and HIV CoinfectionHepatitis and HIV Coinfection
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Non Sero Conversion after vaccination
Nov 27, 2004

Why is it that after two full course of HepB vaccine and follow ups to both [over a period of several years] my blood test STILL show that I am Hep B neg [ie no sero-conversion].

Response from Dr. McGovern

Unfortunately some patients do not seroconvert to the hepatitis B vaccination. It is not well known why that is the case. It is useful that you know your status however, so that if you do have an exposure, you should get immunoglobulin for protection.

Dr. McGovern

Hep-B/Elevated ALT&AST

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