After Liver viopsy
Nov 20, 2004
I 'm male , 35 years old with HBV infection. My HBV DNA 2,000 cp/ml, ALT 25, AFP 6, HB e-antigen negative and positive HB e antobody. I made liver viopsy and releaved mild Fibrosis stage 1.
The question is shall I go for adefovir treatment now? ? When do I have to make again liver viopsy? Shall keep measuring HBV DNA every six months?
Response from Dr. McGovern
Since your ALT appears normal, I would continue monitoring your ALT and your viremia. Once the ALT becomes persistently abnormal, that may be a time to consider treatment. Because you have hepatitis B e antigen negative infection, there is no clear end-point since you cannot follow change of E antigen positive to E antigen negative. Therefore, since your liver biopsy is mild, you do have some time to make decisions. Also, pegylated interferon may also be a consideration since there have been some good studies with this drug for Hep B antigen negative disease. Dr. McGovern
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.