HepB case: failed hepsera, what next?
Nov 8, 2004
Dr Dieterich, I am a chronic HepB patient, tried all three medications, including combination of lamivudine and hepsera the past year, virus came down and slightly up again, now ALT ~45, DNA 4500 copies. My doc suggests to switch to Viread. Should I continue current treatment or switch to Viread? Sounds like there is no long term study done with this medicine. If I developed Hepsera resistance,is Viread going to work at all? Then what next? I heard about L-FMAU and thymosin, are they available, or better? I feel so desparate about the future right now, especially possibility of relapse after treatment, since I have been on medication for 3 years now. Doc, what should I do? Appreciate any help on this.
Response from Dr. Dieterich
We just presented a small paper at the liver meeting in Boston on this subject. Lucas is the first author. 8 patients just like your case were described. We switched them to combination tenofovir(Viread ) and FTC (Emtriva). They are all undetectable now. Actually both medications come together in one pill once per day called Truvada. That is the best treatment for Hepsera "suboptimal responders". Hepatitis B may really be a chronic disease. Relax, as long as we can get it undetectable and keep it there, you should be fine. Stay well! DTD
Get Email Notifications When This Forum Updates or Subscribe With RSS
- What Color Is Discharge From Herpes?
- What Are The Chances Of Spreading Herpes With No Symptoms?
- Ways You Can Get Chlamydia From People Who Have It
- Treating Genital Herpes Scabs
- Risk Of Transmission Of Herpes From A Toilet
- Time Frame After Contracting Herpes Before It Shows Up On An Std Test
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.