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Hepatitis and HIV CoinfectionHepatitis and HIV Coinfection
           
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hiv &hep
Mar 21, 2001

Is HEP B AND C, considered a stronger virus then HIV. I've read that HEP B & C survives for hours outside the body and HIV for less then a few minutes is that a fact. Is it easier to contract HEP then HIV. thanks

Response from Dr. Rodriguez-Torres

HIV, Hep.B and Hep.C are different.HIV and Hep.B virus are transmitted through blood and sexual contact. HCV is transmitted through blood and less commonly sexually.Hep. B is a DNA virus that replicates through a RNA intermidiate.The virus is complicated and encodes four genes: surface, core,pol and X, and give rise to multiple forms of proteins. It replicates very efficiently in the host and can reach titers of 10x9.virions per mil. Hep.C is a small virus of the flaviviridae family.It contains positive sense single-stranded RNA genome.The main characteristic of Hep.C virus is its genetic heterogeneity with up to 100 mayor subtypes. In the host the virus circulates as a mixture of "Quasispecies", this means a mixture of very similar but different genetic mutants.This differences in the genetic and structural composition explain the diverse survival features both to the environment and host defences.



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