|duration effectiveness of Interferon therapy
Jul 13, 2004
Hi..I have genotype I HCV. I've been on Intron A and peg intron therapies. Now I'm on the new infergen/copegus therapy. For seven months the viral load was dropping dramatically, from 11 mil to 1700. My last labs revealed that the VL went up a little to 2000 after a 6 week interval between the last two tests. Have there ever been tests that prove that the virus can be cleared out this slowly? I believe I saw a study that revealed that if the virus is not cleared in 12 weeks it won't be cleared out, is this true? Can we expect other variations of interferons to help us non-responders (or slow responders)?
thank you for your information
Response from Dr. McGovern
You are correct to be concerned that you still have virus at 7 months of treatment. There are studies suggesting that if you haven't cleared by 12 weeks that the chance of virologic "cure" is low.
However, I don't believe there are data regarding 12 week levels and infergen as far as I know.
Also there is another benefit of any interferon therapy. Many studies show that even in patients who do not respond virologically at all, that their liver biopsies look healthier after interferon treatment. I suspect your liver is obtaining benefit since the virus is going down,even if you haven't cleared.
In the future there will also be newer therapies for hepatitis C. Stay tuned.
What's new on the horizon
- Does Muscle Ache Mean I Have Hiv?
- Is Runny Nose A Symptom Of Acute HIV Infection?
- Coated Tongue After Oral Sex Worried I Have HIV
- Erectile Dysfunction After Receptive Anal Sex Without Condom Does It Mean I Have HIV
- Can Bacterial Vaginosis Cause Vaginal Bleeding?
- What Kind Of Sexually Transmitted Infections Does Doxycycline Monohydrate Treat?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.