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Serum Ferritin
Apr 28, 2004

Dear Dr. Dieterich,

I was on Pegintron with Ribavirin treatment last year but did not respond after 6 months. Recently I learned that my Serum Ferritin was very high during treatment and it could dramatically affect the results. It was 364 ng/ml when I started the treatment. Now it jumped to 588 ng/ml. I have two questions in this regard.

1. Is it necessary to do anything to reduce my current Ferritin levels? 2. Should I retry the Pegintron with Ribavirin treatment with iron depletion therapy?

Thanks a lot for your help.

Alex

Response from Dr. Dieterich

Alex,

That is not a high ferritin level. It is common in HCV. I would suggest you try switching brands to peg alfa 2a or Pegasys this time and make sure you take enough ribavirin. It can respond the next time.

Good luck! DTD



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