Feb 3, 2003
If there is a simultaneous co-infection with more than one pathogen (HIV and HepC for instance), what causes lower viremia levels during acute co-infection? Is it the initial immunincompetence and delayed seroconversion that also keeps viremia low until much later? Can viremia levels be high in organs like liver or testes and remain undetectable in blood? Are these lower viremia levels below the level of detection for commercially available assays? Thanx, HCW
Response from Dr. Dieterich
The main issue here is that lower levels of virus like HIV and HCV are still detectable by PCR. There is too much worry about missed diagnoses. Have safe sex and if you slip up get a PCR and that is definitive. Good luck! DTD
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