Treatment of Acute infection.
Sep 20, 2002
I was possibly exposed to HIV and Hepatitis 60 days ago. I am awaiting the results of my hiv pcr. I took hep c anti body and HBV suface antigen & antibody tests at 40 days post exposure-all tests were negative.My question is: If I have contracted Hep C from my risky exposure, what is the prognosis if I treat it immediately(Within 3 months of exposure). What factor will recent hiv infection have on treatment of acute hep c?
Response from Dr. Fried
In order to determine more quickly if HCV infection is present, check HCV RNA by PCR. This should be positive by now. If HCV RNA is repeatedly positive over 3-4 months after the exposure, it is likely that it will become a chronic infection. Recent data suggests a very high likelihood of cure with interferon therapy in the setting of acute HCV (~98%). The impact of recent HIV infection in this situation is not known. Definitely, encourage your doctor to check HCV RNA and discuss the pros/cons of early therapy.
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