|ON LAM (3 months) what next? ADEFOVIR and/or PegIFN
Aug 8, 2002
My profile is as follows:
Diagnosed on Nov 2000. HBsAg POsitive HBcoreAB Positive HBsAB Negative HBvDNA Positive (26.000.000 copies-ml as of Nov 2000). 187.336.000 copies-ml as of Apr 2002). Feb 2002:ALT/AST = 276/126; Apr 2002:ALT/AST = 318/147. I started tratment (LAM) 20 days ago. My question is: I read that after 9 months the risk of getting the mutant YMDD become higher. If I stay for 3 months or until my viral load goes down to at least 18.733 (4 log reduction), it would be a sign that LAM is working and if so, I could switch or add Interferon. (I would like to try PegIFN.) Is this the right approach? What do you recommend? If Adefovir is available in the future, will it be better to try Adefovir than PegIFN? Thanks and kindest regards.
Response from Dr. Dieterich
Adefovir was approved yesterday and should be on the market in a few months and will work if HBV becomes resistant to lamivudine. The results of Peg and lamivudine also seem to be better than either alone. There is no clear best answer now. Combinations of anything will seem to be the answer to HBV like they are for HIV. DTD
Hep C help Me
- Flu Symptoms After Oral Sex Worried I Have HIV
- Itchy Testicles After Touching Used Condom Sign Of HIV AIDS
- Muscle Ache After Anal Sex Bottom Sign Of HIV AIDS
- Rectal Bleeding After Fingering Worried I Have HIV
- Swollen Lymph Glands After Sucking Penis Worried I Have HIV
- How Soon After Can You Test For Std?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.