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Ask the Experts about Hepatitis and HIV Coinfection
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High SGPT and SGOT while taking Pegasys
Jun 12, 2009

Hello,

Why should i have high ALT (302) and high SGOT (185) after my 4th shot of Pegasys 180? I did the test of HBS Ag before treatment and it was 15,700 and after the 4th shot it dropped down to 4,960! I asked my doctor and he said that this is a good indicator that your treatment is working, is this true? What about if my ALT kept rising? Will it have bad affect on my liver?

Thanks,

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   Response from Dr. McGovern

It is very possible that the interferon shots are causing your immune system to fight the hepatitis virus that is in your liver.

That said, I would want you to have careful close monitoring to be certain that these blood tests don't continue to rise.



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