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Fatigue and AnemiaFatigue and Anemia
         
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parvo virus or oi
Nov 1, 2001

Dr Franscino, In your fatigue answere's you mention to check parvo virus , what is that and where can i find out more about it

Response from Dr. Frascino

Hello,

What is it? Parvovirus B19 is a virus that can be an opportunistic infection in folks with immune deficiency.

Where can you find out more about it? Well, how about right here?

It's a relatively common infection. In people with normal immune systems, it causes a rash (erythema infectiosum, "Slapped cheek rash") and fever. This is also called "fifth disease" and is frequently seen in kids.

Adults often complain of joint pains when they contract parvovirus. In most cases, symptoms are mild and resolve within days to weeks. There are other more rare conditions - hydrops fetalis and transient aplastic crisis - but this probably is way more information than you want to know.

The important information for HIV-positive folks is that if our immune systems are impaired or deficient, we may not be able to fight off a routine parvovirus B19 infection. So, instead of a self-limited relatively mild condition, if we lack the appropriate immune system defenses and response, we could develop a persistent parvovirus B19 infection. This can lead to a condition called red-cell aplasia with severe anemia. Diagnosis of parvovirus B19 is made with a blood test. It is most effectively treated with IVIG (intravenous immunoglobulin), which has a good source of neutralizing antibodies. Relapses in patients with AIDS or other conditions associated with severe immunodeficiency are common, but respond to repeated doses of IVIG.

Hope that helps.

Dr. Bob


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