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fat loss or fat gain
May 15, 2008

am in uganda, africa. i have been on efavirenz ,lamivudine andzidovudine for two year. its the drung here in uganda given for free.i havent got any fat loss. is that combination likely to cause fat loss or fat gain? thanks for the spilit you put in us. hope we will over come this epidamic.

Response from Dr. Frascino


Lipoatrophy (fat loss) and lipohypertrophy (fat gain) are still not completely understood. What we do know is that certain drugs are more associated with fat loss than others. The thymidine analogues seem to be the biggest culprits. These drugs include Zerit (D4T) and zidovudine (AZT). Consequently we try to avoid those drugs when possible. Please note not everyone who takes these drugs will get fat loss; however, there is an increased chance of it occurring.

You can read much more about lipoatrophy (fat loss) by reviewing the information in The Body's Lipoatrophy Resource Center, which can be easily accessed on The Body's homepage under "Quick Links."

Good luck.

Dr. Bob

HIV & Hep
Starting with Meds with low VL and High CD4

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