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Toxoplasmosis
Aug 17, 2004

Best treatment or medication for toxoplasmosis

Response from Dr. Frascino

Hi,

Well that depends . . . .

For acute infection pyrimethamine, folinic acid, and sulfadiazine (or trisulfapyrimidine) are usually used. Atovaquone, TMP-SMX, or minocycline are alternative regimens. Corticosteroids are sometimes needed if there is brain edema (swelling).

For suppressive therapy pyrimethamine, folinic acid, and sulfadiazine are preferred.

For primary prophylaxis with CD4 < 100 cells and positive IgG toxo serology, TMP-SMX is recommended until the CD4 count is greater than 200 for three months.

For secondary prophylaxis, TMP-SMX is recommended until the CD4 count is greater than 200 for six months.

So you can see your question is brief, but the response, complex. Your HIV/AIDS specialist should be well trained to advise you which treatment is "best" for your situation.

Good luck.

Dr. Bob


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