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why not
Sep 30, 2002

why can't we transfuse t cells as a defense against hiv?

Response from Dr. Frascino

Hi,

Short question, but it would require a very complex and lengthy reply well beyond the scope of this forum. Briefly, you would have to transfuse your own T-cells; otherwise, the body's immune system would reject them. If you try to grow your own T-cells outside the body with IL2 (I did this as a research protocol years ago), you can't determine which T-cells are infected and which are not. Also, T-cells grown outside the body with a growth factor may not behave the same way as cells your body makes.

Good idea; however, we already tried it. Stay posted for other immune-based therapies that might hold more promise!

Dr. Bob


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