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Dolutegravir risk of fat loss
Apr 7, 2014

I recently was switched from Atripla to Dolutegravir and Truvada. I began treatment with Atripla in Dec 2012 and quickly went undetectable but toward the end of 2013 my VL started slowly rising from 60 to 400. I was found to have no resistance to any medication and my doctor suggested the switch as she has see great results with this combo. I actually have two questions. First, is this a good combination? Second, how common are fat changes with Dolutegravir?

Response from Dr. Pierone

This is a good combination of antiretroviral medications with proven safety and efficacy. The risk of fat loss with this combination should be similar to the risk associated with Atripla.

I hope this information helps and good luck!



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