I've begun experiencing lipoatrophy in my cheeks and recently had pmma injections although have yet to see benefit. I've been on truvada nd viramune for about 3 years. But truvada has been part of my regimen for about 7 years. Is truvada the suspect? What can I switch to? My doc recommended atripla but I've heard that is causing lipoatrophy as well. Will making a switch even help at all. I feel like good diet, supplements as working out have no impact at all to this problem.

Thanks

Hello, and thanks for posting.

Changing from Viramune/Truvada to Atripla would represent a switch from Viramune to Sustiva only since Truvada is part of Atripla. This switch would be unlikely to make any difference in the lipoatrophy. Truvada is less likely than some other nukes to produce lipoatrophy, but this complication may still occur on with this medication. There is no evidence that switching from Truvada to another medication would help lipoatrophy.

If you did not see any benefit from the PMMA there was probably not enough product used. Generally one does not see improvement in results over time with PMMA.

Good luck!