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PMMA - synthetic or bovine?
Jul 26, 2010

Hi, I am 43yo and 7 years HIV + with a regimen of Sustiva and healthy. I, however, have deep wrinkles in my face cheeks and crows feet, and deep line wrinkles in my forehead. I think this is mostly due to HIV. I've read on your forum that PMMA filler is a bovine derivative. However, I emailed Clinic'estetica in Tijuana and they sent a pdf document that says PMMA is synthetic. Do some clinics now use the synthetic PMMA as opposed to the bovine based PMMA? Thank you.

Response from Dr. Pierone

PMMA is poly methyl methacrylate, a synthetic polymer. Microspheres of PMMA have been used as facial fillers worldwide for many years. Examples of different PMMA brands include Metacrill, NewPlastic, and Artecoll. The last time I checked, Clinic'estetica produced their own brand of PMMA.

The only PMMA filler that is available in the United States is Artefill. This product contains PMMA microspheres co-formulated with bovine collagen. The collagen is reabsorbed and the PMMA remains as a permanent filler.

I hope that this information helps and best of luck to you!



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