Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.
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Request for explanation on discordant couples?
Jul 24, 2003
What brings about discordant status where a couple sexually active may have one negative and the other positive?
Is the negative partner truly negative?
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Response from Dr. Remien
Transmission of HIV is dependent on numerous factors (e.g., the strain of virus, the general health of both people, the sex behaviors that take place, genetic factors, etc. etc.). Transmission of HIV does not occur every time there is exposure to the virus. It is possible that someone can be infected with HIV for awhile before they develop antibodies and test HIV+ on an antibody test. However, in general, after a few months of having been exposed to the virus, if the test is negative, that person can consider his or herself to be HIV-.
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