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Positive Man-Negative Woman-Baby?
Nov 6, 2000

I am an HIV+ gay man who has been approached by two different female friends about donating sperm for them to have a child. Is it possible to donate sperm for pregnancy without ANY risk of transmission of the virus? If so, what would be your recommendation on donation?

Response from Dr. Jackson

There is no way to guarantee that sperm from an HIV positive man will not transmit HIV. One can decrease the risk by taking antiretrovirals to decrease viral load to undetectable in the blood, but that does not mean that viral load is undetectable in the semen. Semen also has lymphocytes which can harbor the virus despite the use of potent antiretrovirals. There is also the risk that the antiretroviral may cause genetic defects in your sperm.In vitro fertilization probably also decreases the risk, but again, one could not be certain that all virus had been removed before implantation. In short I would advise against this donation.

BJ

Brooks Jackson, M.D.


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