Sep 15, 2000
Thank you for this forum. How related to tcell counts is remission of lymphoma? If you stay above 200 will it remain in remission or is it higher? Is it related to the areas of attack or in general all the same, like is the bone more likely to recur than the stomach and lungs?
Thanks so much
Response from Dr. Pavia
First a disclaimer. None of us are oncologists. However, the literature, as well as experience shows that a person's chance of going into remission and staying in remission is better if the CD4 count is higher. With many lymphoma, particularly the more aggressive ones, there is a point at which a prolonged remission really means a cure, that there are no more malignant cells around.
I don't think there is a specific minimum number of T cells, but in general, higher is better, and there is a difference between how lymphomas behave in people with T cells higher than 200 and those under 200. We like to optimize control of HIV in patients with lymphoma, especially after an initial response to chemo if they are doing well.
The location of the original location effects the overall prognosis, but not necessarily where a recurrence would crop up. Hope this helps, but make sure to ask your oncologist the same questions.
Andrew T. Pavia, M.D.
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