|Treatment of KS after Doxil and Taxol? What's next?
Aug 18, 2001
My partner has systemic chemo-resistant KS. In the last two years he has undergone radiation therapy, Doxil therapy (failed after 4 months) and now a combination of Taxol and Thalidomide for the last 15 months in addition to HAART (CD4 <50 & viral load undectable). The Taxol is beginning to fail. What if any treatments are available after the Taxol fails?
Response from Dr. Dezube
KS usually responds to the agents you listed, but on occasion resistant KS does develop, In my own practice, such resistance is fortunately quite rare. Sometimes it's a matter of pushing on the Taxol a bit harder. Is he getting it every two weeks? In patients, who get Taxol every 2 weeks, it's often necessary to give G-CSF (neupogen) and Procrit to keep the white cells and red cells robust. Depending upon your geographic location, there are a series of inestigational angiogenesis inhibitors (agents which block new blood vessel formation) which may be available to him. Other chemotherapy agents which work for KS are the combination of bleomycin/vincristine or the single agent vinorelbine. His oncologist should be familiar with these agents. If you want, his oncologist can call me. I'm listed with the oncology societies. GOOD LUCK.
Lymphoma and a CD4 count of 271-- Is it possible to come down with PCP pneumonia?
Do HIV drugs prevent lymphoma from popping up?
- Can You Transfer Hiv Through Aids Rashes And Bumps?
- If I Got Vaccine Against Hep B Should I Be Reactive To Testing?
- White Bumps Vagina Hpv Signs
- When Will A Woman Find Out She Has Gonorrhea?
- What Would Cause False Positive Syphilis Blood Test?
- What Is The Incubation Period For Gonorrhea?
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.