|Chemotherapy and radiation for anal cancer? Can HIV positive patients get these therapies?
Aug 7, 2001
Are chemotherapy and radiation for anal cancer contraindicated in HIV positive patients?
Response from Dr. Dezube
HIV-positive patients are at an increased risk for developing anal cancer as a consequence of HPV (human papilloma virus infection). We recommend anal PAP smears as a way of catching such lesions early (please see my separate response on Anal PAP smear posted earlier this month). On occasion, precancerous lesions do indeed become cancerous. The cancerous lesions are treated with a combination of chemotherapy (typically 5-fluorouracil, mitomycin) and radiotherapy. Not only are they NOT contraindicated in HIV positive patients, they are the treatment of choice once invasive cancer develops. HIV positive patients often tolerate these treatments less well than HIV negative patients. Nevertheless this is the best treatment for this condition and it has a very good success rate of sparing patients from needing a colostomy bag. Patients who receive this combination of chemotherapy and radiation should NOT be taking AZT (zidovudine, combivir) since this anti-retroviral medication does NOT mix well with chemotherapy. BD.
Negative Gallium Scan. Do I need to complete the chemotherapy?
How does KS look? Can KS blanch (turn white wehn you press on it)?
- Is Painful Urination A Symptom Of HIV?
- Is Sore On Penis An Early Sign Of HIV?
- Stinging Pain During Seroconversion
- Burning Penis After Oral Sex Hooker What Are The Chances Of HIV
- Dry Mouth After Swallowing Precum What Are The Chances Of HIV
- Hairy Tongue After Oral Sex Form Sex Worker What Are The Chances Of HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.