The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

AIDS-Related CancersAIDS-Related Cancers
Rollover images to visit our other forums!
  • Email Email
  • Glossary Glossary

monoclonal gammapathy; what's the significance
Mar 25, 2001

Last year I was diagnosed with Lymes Disease. As part of the exam, blood work was done at which time an abnormal protein band was detected in the gamma globulins. I went to an oncologist who conducted further test. My abnormal protein band is .05 as of February of this year. Also, my white blood cell count was 3.7 thous/mcl, HDL-cholesterol = 226 and LDL-cholesterol = 154. All other lab findings were in range, negative or non reactive.

I am a 46 y/o black male, 220 lbs. No prior medical history of consequence. My primary Dr. said there is nothing to worry about, she will monitor it annually during my physicals.

Only because I was recently denied reinstatement of my life insurance due to a history of monoclonal gammapathy I am now researching the cause and potential of the diagnosis. Please explain what this means from an insurability standpoint.

Thank you in advance, RD

Response from Dr. Dezube

Dear RD: I feel for you. You basically have a laboratory abnormality (monoclonal protein) which can't be ignored, even though most likely there is indeed nothing to worry about. Monoclonal proteins are sometimes the first sign of cancer so I can understand your insurance company's reluctance to cover you. More often than not (about 80% of the time), the monoclonal proteins tend to be NOT significant. You'll know only with time. You should have your monoclonal proteins monitored on a regular basis, a few times a year (two or three times). Hopefully in time your monoclonal protein will go away by itself or at least not rise. I have many patients in your position. You may need to look for a different insurance company. From a medical standpoint, nothing else needs to be done at this time, though some oncologists would perform a bone marrow biopsy to be sure of what you have. I personally would recommend rechecking the protein in about 3-4 months. If it is the same or less, I would do nothing. If it's higher, I would do a bone marrow at that time. Hope this helps. In short, I don't think you have to worry too much, but I can't give you a guarantee. BD.

Spots on skin
Swollen glands- Does it mean I have HIV

  • Email Email
  • Glossary Glossary



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint