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KS and Lungs; will y KS rebound after stopping chemotherapy?
Jan 20, 2003

Dr. Dezube,

I wanted to ask you a question I didn't see posted in the past unless I just missed it. Last year in November I became very sick and hospitalized with related HIV/AIDS symptoms. One of the occurring problem was I have KS on my lungs. I have been going to get Doxil treatments but my doctor has now stopped the treatments basically saying to me "i can't sure what you have" which didn't sit well with me of course. My fear now is since I stopped the Doxil will the KS rebound and grow within my lungs? The skin KS i had disappeared quickly. I am on antiviral drugs (Zerit, Kaletra and Epivir) as well as number of vitamins. Considering I've never been sick a day in my life beyond a cold before last years diagnosis I'm still totally freaked out by this horrid disease and its potential so I may be over reacting. Also referring to my cancer doctors comment do you think I should be searching out a new doctor? he's supposed to be one of the best. Thank You, Matt

Response from Dr. Dezube

Dear Matt: Your doctor's management of your case sounds very reasonable. I too treat my patients, who have KS in the lung, with chemotherapy. I too usually stop after a while and see what happens. I typically give 6 rounds of chemotherapy before stopping the chemotherapy. If you are taking HIV drugs such as zerit, kaletra and epivir, it is very possible that the KS in your lungs won't come back. The higher your CD4 count and the lower your viral load, the more likely it is that your KS won't come back. If the KS does come back, then at that time you can always start back on chemotherapy. If the KS responded to the initial round of chemotherapy, then it typically responds to the second round of chemotherapy.


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