The Body: The Complete HIV/AIDS Resource
Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App 
Professionals >> Visit The Body PROThe Body en Espanol
Ask the Experts About

AIDS-Related CancersAIDS-Related Cancers
Rollover images to visit our other forums!
  • Email Email
  • Glossary Glossary

HLA matched bone marrow from HIV non-progressors?
Mar 2, 2001

Dear Doctor: I noticed in the July edition of the Journal of Acquired Immune Deficiency that an HIV-infected patient has been treated successfully with intensive chemotherapy combined with a bone marrow transplant. The transplant came from an HLA matched sibling. What I'm wondering is whether in the future it may be possible to use HLA matched bone marrow from people who are HIV non-progressors, and or people with one of the two genetic markers for HIV resistance; (CCr4, CXr5). I read that out of 200,000 racially similar candidates, that the odds are 40-50 of finding an HLA matched. It's a big project, but potentially a registry of these categories of HIV resistant individuals willing to donate could be made.

Response from Dr. Dezube

A few years ago, bone marrow transplantation in HIV-infected patients was unthinkable. We will indeed be seeing more and more reports of it. Currently however it remains quite a toxic procedure. Only time will tell how this will pan out in the HIV-infected community. The cancer community is now testing the concept of "mini-transplants"(also known as "Transplant-Lite") which is a less toxic procedure, but equally effective. Science is exciting because it leads to the exploration of new frontiers. Who knows what's in store for HIV'ers??

possible symptoms of cancer?
Does re-occuring shingles pose higher risk of KS?

  • Email Email
  • Glossary Glossary



This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.

Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.

Review our complete terms of use and copyright notice.

Powered by ExpertViewpoint