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husbands lymphoma returned after stem cell transplant
Mar 2, 2001

My husband has NHL for a year and a half. He has had lots of different chemos. He had a stem cell transplant 6 months ago but the cancer has returned. He is currently receiving a chemo every 4 weeks that's given while hospitalized for 3 days. Its the only one that seems to shrink the tumors. The plan is to keep the cancer under control for the next 6 months and then have another transplant, this time using a donor instead of his own stem cells. My question is, what are his chances of this working? and has anyone ever been in a long remission after a second transplant? Is there anything else we can try? Thank you Barbara

Response from Dr. Dezube

Dear Barbara, clearly your husband is in a difficult situation now that his cancer has returned after a stem cell transplant. Occasionally a second transplant works, particularly if it is from a donor instead of his own stem cells. The side effects of a donor transplant may at times be more severe than the original transplant. Many centers are switching to a procedure called "mini-transplant", also known as "transplant-Lite". Without knowing more of the specifics, it's hard to know if your husband is a candidate for such a procedure. These mini-transplants are often better tolerated and are quite effective. These mini-transplants work by harvesting the immune system; however they only work for certain types of lymphoma and a lot depends upon the ability of your husband to get a suitable match. His oncologist should be able to fill you in about this procedure. GOOD LUCK, BD.

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