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Response from Dr. Dezube

White cells are the the cells that help fight off infection. A white count of 2600 (also referred to as 2.6) is indeed low, though not very low. Typically the white count should be above 4000 (also referred to as 4.0). Sometimes a bone marrow examination is performed to help figure out what's going on. It's difficult to comment as to whether or not you should have a biopsy without knowing much more about your situation.
Are you HIV positive? If so, do you have symptoms (fever, chills, night sweats, weight loss). If so, then a low white count could be a sign that something else is going on.
Are you an any medication which could lower your white count? If you are taking AZT, then a low white count is to be expected.
Are you an African-American? African-Americans typically have lower white counts than Caucasians. The lower white counts in African-Americans usually cause no problems and represent nothing more than an interesting laboratory finding.
Have you recently been ill. It is not unusual that after a viral infection (e.g. the flu) that the bone marrow temporarily slows down. As a consequence, you can get a low white count on that basis.
It's also important to know how long you've had a low white count. It is not unusual for low white counts to be transient in nature, lasting typically a few weeks. Have you seen a hematologist? (S)he should be able to help you assess the situation.
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