Please Note: Due to volume considerations, not all questions can be answered. Questions most likely to be answered will be those of general interest to a broad group of visitors to this forum. Questions pertaining to a specific case; requests for diagnosis, medical advice, or second opinion; or requests for opinions about untested alternative therapies will generally not be answered.
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New diagnosis of Non-Hodgkin's Lymphoma-- What should my treatment be?
Mar 15, 2003
Hello, HIV Positive and on HAART with T-Cells just under 400 and and VL at 70, I have just been diagnosed with Non-Hodgkins Lymphoma, High Grade, B Cell. Looking at CHOP-R therapy possibly followed by stem cell or bone marrow transplant. I know we need an aggressive course of therapy, and what is yur reaction to this approach? You have the best HIV website around. Thanks for the good work. Gary
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Response from Dr. Dezube
Dear Gary,
The good news about your lymphoma is that it is very treatable. I have many many patients who are long term survivors. There are several different treatment regimens with good track records. I too use CHOP-R, the one that is recommended to you, for patients in your CD4 cell bracket. (I'm a bit more reluctant to use Rituxan in patients with low CD4 cell counts). CHOP-R contains Rituxan, Cytoxan, Adriamycin, Vincristine, and Prednisone. Typically we give it 6 times. Plase note that I do NOT recommend stem cell or bone marrow transplant for most patients like you. Is there something in your history/story which I'm missing that would have lead to your oncologist to make such a recommendation? There are simply not enough data to support transplant in your setting, and most of the patients with your disease do well without a transplant.
Good luck. You hopefully will do quite well.
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