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How does HIV stay even when undetectable
May 31, 2008
I know that viruses can commit to one of two pathways. Laten and Lytic. In viruses (general) they can inject the DNA or RNA and it becomes part of the Host genome, but if HIV binds to CD4 presenting cells how does it become part of the human genome. CD4 presenting cells don't replicate but rather activate, so shouldn't people be able to erradicate the virus on prolonged meds?
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Response from Dr. Moyle
HIV 'hides' integrated in resting CD4 cells. When these cells reactivate after exposure to their recall antigen, HIV replication commences. These long lived memory cells may exist throghout an individuals life, making eradication with current treatment impossible. Scienists are looking at ways round this but for the time being its keep taking the tablets
regards
Dr Moyle
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